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Drugs that inhibit CYP2D6 action, such as paroxetine and quinidine, might induce decreased clearance of oxycodone which could lead on to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.Browse the Medication Guideline provided by your pharma